Fabrication and Characterization of Persea Gratissima Oil Loaded Chitosan Nanoparticles and Investigation of Its Neuroprotective Effects

Persea gratissima known as avocado is a valuable plant. P. (PgO) oil used in traditional medicine to treat several health problems because of its numerous biological properties. source phytosterols and has effects antimicrobial, anti-inflammatory, anti-oxidant neuroprotective activities for vitro vivo models. The aim this study synthesize characterize the PgO loaded chitosan nanoparticles investigate vitro. According effects, we prepared nanocapsulation with using by ionic gelation method. Mitochondrial activity gratissima, were investigated XTT method on SH-SY5Y L929 cell lines comparatively. Obtained results showed that have proliferative effect line agent no side both lines. In conclusion are promising neural regeneration candidate further evaluation potential neurodegenerative disease drug formula.